This study is testing a new treatment called G207 for kids with recurring brain tumors in the cerebellum (part of the brain). G207 is a special type of virus called an oncolytic virus, which means it can attack and kill cancer cells without harming normal cells. The study will also see if using a tiny amount of radiation helps the virus work better. It's supported by the FDA OOPD (Food and Drug Administration Office of Orphan Products Development).
- The study is for kids aged 3 to 21 with specific brain tumors that have come back or haven't responded to other treatments.
- Participants may get just the virus or the virus plus a small dose of radiation.
- Doctors will closely check the treatment's safety and gather early results on how well it works.
To join, patients must have tried other treatments first, be in good health (like having enough blood cells and kidney function), and not be pregnant. They also need permission from a doctor or guardian. Some kids won't qualify, like those with certain infections or taking specific medicines. The study will help researchers learn more about fighting these tough-to-treat tumors.