Image

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

Exploring IDE892 for certain advanced solid tumors treatment.

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study tests a medicine called **IDE892** for certain advanced cancers, either alone or with another drug, **IDE397**. Some cancers lose a gene called MTAP, which this study focuses on. Adults 18+ with MTAP-deleted tumors can join if their cancer has grown after standard treatment. They must be able to give blood and tissue samples for tests and agree to follow study rules. Exclusions include recent cancer treatments, certain heart or brain issues, and specific medical conditions.

  • The study length and number of visits will vary based on individual treatment plans.
  • Participants may receive the study drug IDE892 alone or with IDE397.
  • Potential risks include side effects from the treatments and the need for regular testing and monitoring.
Print
Study details
    NSCLC Adenocarcinoma
    Gastroesophageal Cancer (GC)
    Gastric Adenocarcinoma
    Adenocarcinoma of Esophagus
    Squamous Cell Car. - Esophagus
    Urothelial Carcinoma (UC)
    Bladder Cancer
    Mesothelioma
    Pleural Mesothelioma
    Peritoneal Mesothelioma
    Non-Small Cell Lung Cancer NSCLC
    Pancreatic Cancer
    Biliary Tract Carcinoma

NCT07277413

IDEAYA Biosciences

15 August 2026

Contact a study center
Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.