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Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC)

Exploring new treatment options for GBM and PDAC patients.

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study tests a new imaging drug called 203Pb-RMX-VH-PIB for brain tumors (glioblastoma multiforme, GBM) and pancreatic cancer (pancreatic ductal adenocarcinoma, PDAC). It checks how the drug moves in the body (biodistribution) and how much radiation organs receive (dosimetry). Patients will get one intravenous (IV) injection of the drug and have several scans using a special machine called SPECT/CT to take pictures of their insides. Doctors will also monitor blood, urine, heart rhythm, and vital signs for safety. This study aims to enroll 20 patients who meet specific health criteria, like having a certain size of tumor or being stable without recent chemotherapy. Participants' health will be followed for 30 days to check for any side effects.

  • Participants receive one IV injection and several scans.
  • Study involves monitoring for 30 days for any side effects.
  • Health criteria must be met for participation.
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Study details
    Glioblastoma Multiforme (GBM)
    Pancreatic Ductal Adenocarcinoma (PDAC)

NCT07733674

Radiomedix, Inc.

15 August 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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