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Breath Research Narrow Validation for Gastrointestinal Cancer Detection

Join our study on breath tests for detecting gut cancer.

Recruiting
18 years and older
All
Phase N/A

The study aims to create a simple breath test to find cancers in the digestive system, like in the oesophagus (food pipe), stomach, liver, pancreas, and bowel. These cancers can cause symptoms that are hard to tell apart from less serious illnesses, making it tough to catch early. The breath test looks for tiny particles called volatile organic compounds (VOCs), which are often linked to these cancers. If the breath test shows a positive result, the patient can get more tests quickly. This might help find cancer sooner, allowing for better treatment options.

Participants will offer a breath sample, usually before a planned hospital procedure, and fill out a short health history form. Some might drink a nutritional supplement before a second breath test. This helps check if the breath test is accurate.

  • Participants should be at least 18 years old.
  • Cannot join if they have had treatments like chemotherapy or surgery for cancer recently.
  • Some participants will drink a special nutrient drink before testing.
Study details
    Oesophageal Squamous Cell Carcinoma
    Oesophageal Adenocarcinoma
    Gastric Adenocarcinoma
    Pancreatic Ductal Adenocarcinoma (PDAC)
    Cholangiocarcinoma
    Hepatocellular Carcinoma (HCC)
    Colorectal Adenocarcinoma

NCT07714538

Imperial College London

12 September 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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