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A Phase II Study Evaluating BMS-986504 in MTAP-deleted Pancreatic Cancer

Join a study testing a new drug for pancreatic cancer.

Recruiting
18 years and older
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Phase 2
This study is exploring a new treatment called **BMS-986504** for people with a type of pancreatic cancer called **MTAP-deleted PDAC**. There are three groups in the study. The first group will receive BMS-986504 along with chemotherapy before and after surgery. The other two groups will receive BMS-986504 with standard chemotherapy. **Chemotherapy** is medicine that helps stop cancer cells from growing. **PDAC** stands for pancreatic ductal adenocarcinoma, a common type of pancreatic cancer. To join the study, you must be at least 18 years old and have a specific genetic change called **MTAP deletion**, which can be checked through a simple test on your cancer tissue or blood. You also should not have other major health issues, including heart problems or other active cancers. **Key Points to Consider:** - The study will involve regular visits and follow-ups for treatment and tests. - Participants must agree to use effective birth control methods. - There may be risks, such as side effects from the treatment, but the study aims to find out if this new treatment can help control the cancer. For more information, it is important to discuss the details with a healthcare provider.
Study details
    Phase 2 Study
    BMS-986504
    MTAP-deleted Pancreatic Cancer

NCT07283705

M.D. Anderson Cancer Center

29 August 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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