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A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

Exploring new treatments for advanced tumors with MTAP deletion.

Recruiting
18 years and older
All
Phase 2
This study is testing a new medicine called **BMS-986504** for people with advanced or spreading solid tumors that have a missing part of a gene called **MTAP**. A gene is like a small instruction manual inside your body that helps it function. Sometimes parts of these manuals are missing, like MTAP, which can affect how your body grows cells. The study has two parts: one where BMS-986504 is used alone (monotherapy), and another where it's combined with other cancer-fighting drugs. **Key Points:** - **Duration and Visits**: The study has different parts, but it doesn't specify how long each takes or how many visits are needed. You should ask the study team about this. - **Treatment**: You'll receive BMS-986504 alone or with other drugs. Your doctor will help decide what's best for you. - **Eligibility**: You must have a specific type of cancer and meet certain health criteria. You cannot join if you've had certain treatments before or have specific health issues, like brain problems or active viral hepatitis. Before deciding to participate, discuss any concerns or questions with your doctor to make sure this study is the right choice for you.
Study details
    Solid Tumors

NCT07492680

Bristol-Myers Squibb

29 August 2026

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