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Remote Ischemic Conditioning for Sleep Disturbances and Other Non-motor Symptoms in Parkinson's Disease

Exploring new ways to help Parkinson's sleep and symptoms.

Recruiting
50-70 years
All
Phase N/A
This study explores if *Remote Ischemic Conditioning* (RIC) can help with sleep problems and other non-motor symptoms in people with Parkinson's Disease (PD). RIC involves using a cuff to create brief periods of low blood flow and then restoring it, similar to exercising the body. The study will include 48 PD patients with insomnia (trouble sleeping) and compare two groups: one receiving active RIC and another receiving a fake (sham) RIC. Participants will keep taking their regular Parkinson's medications during the study. **Key Points:** - The study lasts 7 days with RIC treatment twice daily. There will be follow-up visits. - Participants will undergo various tests like sleep studies and brain scans before and after the treatment. - The study will check if RIC improves sleep and other non-motor symptoms, such as mood and quality of life. **Eligibility:** People with PD aged 50-70, diagnosed for 5 years or less, with trouble sleeping, and stable on their medications can join. Those with other major health issues or sleep disorders are not eligible.
Study details
    Parkinson Disease (PD)
    Insomnia

NCT07299240

Jiangsu Province Nanjing Brain Hospital

2 August 2026

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