The **Progressive Supranuclear Palsy (PSP) Clinical Trial Platform (PTP)** aims to test new treatments for PSP, a brain disorder that affects movement and balance. This study is a *platform trial*, meaning it will keep going as new treatments are developed. Multiple treatments will be tested at the same time or one after the other. Each treatment is tested against a *placebo*, which looks like the treatment but has no active ingredients. **Key Points:** - **Length & Visits:** Participation involves multiple visits over time as new treatments are tested. - **Randomization:** Participants have an equal chance of receiving the actual treatment or a placebo. - **Eligibility:** Participants must meet specific health criteria, like being able to walk 10 steps with minimal help. This trial is open to people diagnosed with PSP and will help determine the safety and effectiveness of new treatments. Participants should not be pregnant or breastfeeding and must be willing to follow the trial procedures. If you're interested, make sure you're comfortable with the possibility of receiving a placebo and are able to visit the trial center as needed.