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A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide for Multiple Myeloma, Newly Diagnosed AL Amyloidosis, and High-risk Smoldering Multiple Myeloma or JNJ-79635322 in Combination With Pomalidomide for Multiple Myeloma

Exploring new combinations for multiple myeloma treatment options.

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is testing a new treatment (JNJ-79635322) for Multiple Myeloma, a type of blood cancer. Researchers want to figure out the best dose and schedule when this drug is used with other drugs like daratumumab, lenalidomide, or pomalidomide. The goal is to find the safest and most effective way to use these drugs together. To join, you need to have multiple myeloma and meet certain health conditions. You cannot join if you have serious health issues or have had certain treatments in the past.

  • Study involves different treatment groups and may require several visits.
  • Participants must have been treated for multiple myeloma before or be newly diagnosed.
  • There may be some risks, so eligibility criteria are strict.
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Study details
    Multiple Myeloma
    Smoldering Multiple Myeloma
    Immunoglobulin Light-chain Amyloidosis

NCT06768489

Janssen Research & Development, LLC

17 October 2026

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