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A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

Studying Donanemab for early memory problems.

Recruiting
55-85 years
All
Phase 2
Study Overview:
This study looks at how well a medicine called donanemab helps people with early memory and thinking problems. The study will last for about one and a half years. The main goal is to see if the medicine can slow down problems with thinking and daily activities. Eligibility:
To join, participants should have had memory problems for at least six months and show signs of a condition called dementia with Lewy bodies. They need to have a score of 20 or higher on a test called the Montreal Cognitive Assessment (MoCA). Participants also need to have certain results from blood and spinal fluid tests. They should have someone they know well to help with the study. Key Points:
  • The study will last for 1.5 years.
  • Participants need to have a reliable study partner.
  • Certain medical conditions or history may prevent participation.
Study details
    Cognitive Dysfunction
    Lewy Body Disease
    Synucleinopathies
    Amyloid

NCT07589595

Eli Lilly and Company

17 October 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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