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A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

Testing a new CAR-T therapy for certain types of blood cancers.

Recruiting
6 years and older
All
Phase 2

The T-RRex study is testing a new treatment called WU-CART-007 for people with a type of blood cancer known as T-Cell Acute Lymphoblastic Leukemia (T-ALL) or Lymphoblastic Lymphoma (LBL). These cancers affect the blood and immune system. The study is in Phase 2, which means it's looking at how well the treatment works. Patients in this study have cancer that has come back or hasn't responded to other treatments. The goal is to see if WU-CART-007 can help make the cancer undetectable, known as Minimum Residual Disease (MRD) negative.

  • The study is open to patients 6 months and older, in good health with specific types of blood cancer.
  • Participants cannot have had previous anti-CD7 therapy or certain health conditions.
  • This is a single-arm study, meaning all participants receive the same treatment.

If you join, you will receive the treatment and be monitored by doctors at various locations to check its effectiveness.

Study details
    T-cell Acute Lymphoblastic Leukemia
    Lymphoblastic Lymphoma

NCT06514794

Allotera Therapeutics

17 October 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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