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Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease

Exploring hydroxychloroquine effects when stopped in elderly lupus patients.

Recruiting
55 years and older
All
Phase 3

Study Overview: This research is about stopping a medicine called Hydroxychloroquine (HCQ) in older people (60+ years) with lupus, a disease where the body attacks its own tissues. While HCQ helps control lupus, it can harm the eyes if used for a long time. The study checks if patients can safely stop taking HCQ without their lupus getting worse.

Key Points for Participants:

  • Participants must be 60 years or older, have stable lupus, and have normal eye tests.
  • The study lasts one year, with check-ups every three months.
  • Participants will either continue HCQ or take a placebo (a pill with no medicine).

Eligibility: To join, you need to have stable lupus, not be taking other immune-suppressing drugs, and be willing to follow the study rules. You should not have eye damage or recent severe lupus flares.

Study details
    Systemic Lupus Erythematosus

NCT05799378

NYU Langone Health

17 October 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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