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A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1

Testing a new HIV-1 treatment option compared to standard care.

Recruiting
18 years and older
All
Phase 2
Study Summary: This study looks at HIV-1 treatments in people whose virus is under control. It has two parts. In Part A, researchers will compare two treatments: a new combination of drugs called GS-3242 and Lenacapavir (LEN) given as shots, versus a current medication called Biktarvy (B/F/TAF—this is a combination of three medicines: bictegravir, emtricitabine, and tenofovir alafenamide). This part lasts until Week 35. Part B compares the same treatments but ends at Week 26. Key Points:
  • This study involves switching medications and requires regular doctor visits for shots.
  • Participants must have been on Biktarvy for at least 6 months with low virus levels.
  • People who have used certain HIV treatments before cannot join this study.
Note: Participation is voluntary, and you should carefully consider eligibility and study requirements before joining.
Study details
    HIV-1-infection

NCT07645287

Gilead Sciences

17 October 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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