Image

Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea

Testing Rifaximin with rehydration for kids' diarrhea.

Recruiting
6-12 years
All
Phase 4

This clinical trial is for children aged 6 to 11 with sudden diarrhea, possibly from bacteria. Diarrhea means having loose stools. The study compares two treatments: one group will take a medicine called rifaximin (200 mg) along with oral rehydration therapy (ORT), while the other group will only receive ORT. ORT helps to replace lost fluids, which is important when someone has diarrhea.

The study aims to find out how rifaximin moves in the body and if it is safe and effective for kids. Participants will take rifaximin or just ORT for 3 days. They will visit the clinic up to 4 times over 5 days and have 4 follow-up phone calls. Children in the rifaximin group will give blood samples on the first and third days to study how the drug is processed. All participants will provide stool samples to check for bacteria.

  • The study requires up to 4 clinic visits and 4 follow-up phone calls over 5 days.
  • Participants in the rifaximin group will give blood and stool samples.
  • Participants will keep a diary of their stool frequency and any side effects.
Study details
    Diarrhea
    Gastroenteritis
    Bacterial Infection
    Acute Diarrhea

NCT07285785

Bausch Health Americas, Inc.

17 October 2026

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team


Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race*
Are you a healthy volunteer
Ethnicity*
Are you a healthy volunteer
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.