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STN-tTIS With Different Intervention Intervals Versus Standard Medical Treatment for Parkinson's Disease

Comparing Parkinson's treatments: STN-tTIS vs. standard care.

Recruiting
50-85 years
All
Phase N/A

This study focuses on Parkinson's disease (PD), which is a condition affecting movement and other body functions. The study compares a new method, STN-tTIS (subthalamic nucleus-targeted transcranial temporal interference stimulation), with traditional medication for PD. STN-tTIS is a non-surgical way to stimulate the brain to help improve movement symptoms. The study aims to see if different frequencies of STN-tTIS (once, twice, or five times a week) work better than just medication and how long the effects last. Participants will be randomly assigned to receive either STN-tTIS or continue with their regular PD medication for two weeks. They will be checked for symptoms and other health aspects during and after the treatment.

  • The study lasts 4 weeks in total: 2 weeks of treatment and 2 weeks of follow-up.
  • Participants will either receive STN-tTIS or their usual medication.
  • Assessment includes both movement and non-movement symptoms.
Study details
    Parkinson's Disease (PD)

NCT07774312

Ruijin Hospital

29 August 2026

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