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Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD

Study on breathing exercises for Parkinson's disease. No treatment guaranteed.

Recruiting
40-75 years
All
Phase N/A

This study is testing if a special breathing session can help people with Parkinson's disease (PD) breathe, speak, and cough better. Parkinsonism affects parts of the brain that control muscles, making it hard to breathe and talk. Two breathing methods will be tested: AIHH (acute intermittent hypercapnic hypoxia) and AIHN (acute intermittent hypercapnic normoxia). Hypercapnia means having more carbon dioxide in the blood. Hypoxia means low oxygen levels, and normoxia means normal oxygen levels.

Key Points:

  • This is a one-time session study.
  • No current participation in another research study is allowed.
  • Participants must be 40-75 years old.

To join, you must have Parkinsonism, be able to walk 10 feet, and be cleared by a doctor. You should not join if you have other neurological conditions, severe illness, or are pregnant. Smoking or vaping in the past 5 years is not allowed. This study is for people who can follow directions and are willing to avoid donating blood during the study.

Study details
    Parkinson Disease
    Parkinsonism

NCT07674264

University of Florida

29 August 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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