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A Comprehensive, Multimodal Characterization of Prodromal PD in Subjects With RBD

Study on early Parkinson's signs in people with REM sleep disorder.

Recruiting
18 years and older
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study aims to understand early Parkinson's disease (PD) by examining people with REM Sleep Behavior Disorder (RBD), a condition where people act out dreams due to brain changes. Over 80% of those with RBD might develop PD or similar conditions. Researchers will recruit 50 individuals with RBD and 50 without major mental or brain diseases, matched by age and gender. They will use advanced brain scans and heart tests to find early signs of PD. The study lasts until enough data is collected after ethical approval.

  • Participation involves: Brain scans, sleep tests, and heart function assessments.
  • Eligibility: Must be able to give consent; RBD verified by sleep tests.
  • Exclusions: Metal implants, pacemakers, drug abuse, certain medical conditions.

The results may lead to better early diagnosis and treatment for PD, improving future care for those at risk.

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Study details
    REM Sleep Behavior Disorder
    Synucleinopathies
    Parkinson's Disease (PD)
    Prodromal Parkinson's Disease

NCT07790744

Danish Research Centre for Magnetic Resonance

5 September 2026

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