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A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

Exploring Votoplam's effects in Huntington's disease patients.

Recruiting
21-70 years
All
Phase 3

This study looks at a medicine called votoplam to see if it helps people with early Huntington's Disease (HD), a disorder that affects the brain. The study will last up to 36 months, but not everyone will be in it for the full time. There are three parts: a Screening Period to see if you can join, a Double-blind Treatment Period where you might get votoplam or a placebo (a pill that looks the same but has no medicine), and a Safety Follow-up Period to check on your health after the study ends.

  • The study can last up to 3 years, but not all people will stay that long.
  • You need to be between 21 and 70 years old to join.
  • You cannot join if you have certain health issues or are pregnant.

Before joining, you need to sign a consent form if you agree to participate. This form explains everything about the study. Some people will get the real medicine, while others will get a placebo to compare results. Participants' health will be monitored throughout the study to ensure safety.

Study details
    Huntington Disease

NCT07326709

Novartis Pharmaceuticals

10 October 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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