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A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Evaluating IV Prasinezumab for early-stage Parkinson's safety and effectiveness.

Recruiting
50-85 years
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study tests prasinezumab, a medicine given through a vein (IV), for people with early-stage Parkinson's disease (PD). PD is a brain disorder that affects movement. Participants will either receive prasinezumab or a placebo (a harmless pill or injection that looks like the medicine but isn't) to see if it helps treat PD. This study also checks if the medicine is safe and how it moves in the body, called pharmacokinetics (PK). To join, you must weigh between 88-242 pounds and have a PD diagnosis. You should also already be taking levodopa, a common PD medicine.

  • Length and Visits: Participants will have multiple visits over the study period.
  • Compensation: Some form of compensation may be provided for participation.
  • Risks: Possible side effects from the medicine and IV procedure.

Not everyone can join. If you have other serious health problems or are pregnant, you can't participate. If you're interested, talk to your doctor to see if this study is right for you!

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Study details
    Parkinson's Disease

NCT07174310

Hoffmann-La Roche

11 October 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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