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Optimizing Adaptive DBS for Parkinson's Disease

Exploring new DBS methods for Parkinson's relief.

Recruiting
18 years and older
All
Phase N/A

Parkinson's disease (PD) affects movement, causing symptoms like slowness, stiffness, and tremor. Deep brain stimulation (DBS) is a treatment that helps improve these symptoms. There is a new type called adaptive DBS (aDBS) which adjusts automatically based on brain activity. This study examines if using long-term brain recordings during daily life can improve aDBS programming. Participants will first be tested in a clinic to identify brain signals related to their symptoms. Then, brain activity and symptoms will be monitored during everyday life using the implanted DBS device. Participants who show suitable brain signals will join a study to compare three stimulation methods: conventional DBS, current adaptive DBS, and improved adaptive DBS using home recordings.

  • This study lasts several months and involves both clinic visits and at-home monitoring.
  • Participants must have stable Parkinson's symptoms and DBS settings before starting.
  • Participation involves wearing a smartwatch and using a smartphone app to track symptoms.
Study details
    PARKINSON DISEASE (Disorder)

NCT07798271

University of California, Davis

6 September 2026

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