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Connectomic Guided DBS for Parkinson's Disease

Exploring new DBS methods for Parkinson's symptoms.

Enrolling By Invitation
18 years and older
All
Phase N/A

Parkinson's disease (PD) can cause tremors and movement problems. **Deep Brain Stimulation (DBS)** is a surgery approved by the **US Food and Drug Administration (FDA)** to help treat these symptoms when medicine doesn't work well. The study aims to improve DBS by using advanced imaging called **connectomic models**. These models help doctors find the best places in the brain to target for better tremor control without causing bad side effects like dyskinesias, which are unwanted movements. The focus is on the **subthalamic nucleus (STN)**, a part of the brain important for movement. This research might make DBS treatment more precise and easier to set up, and it might reduce the number of doctor visits needed for adjustments.

  • The study uses information from routine care and intervention study data.
  • Participants must be 18 or older with Parkinson's disease and have had DBS for at least three months.
  • Excludes those without a specific type of head scan or who received DBS recently.
Study details
    Parkinson Disease
    Tremor
    Dyskinesias

NCT06618157

Duke University

12 September 2026

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