Monoamine Oxidase B (MAO-B) is a special protein in the brain. This study looks at how a special scan called 18F-FPyCO/SMBT-1 PET/CT can help find diseases linked to MAO-B. A PET/CT scan is a type of imaging test that helps doctors see inside the body. It combines two scans: a Positron Emission Tomography (PET) scan and a Computed Tomography (CT) scan. The study focuses on people with certain brain diseases, especially those related to a protein called Tau.
The study measures how the scan picks up these diseases using something called maximum standard uptake value (SUVmax), which helps show how much of the scan material is taken up by parts of the body. The study will also look at how accurate the scan is by checking its sensitivity (ability to correctly identify those with the disease), specificity (correctly identify those without the disease), and other measures.
- Duration: The study does not specify a set length.
- Participants: Must be 18 or older and able to give consent.
- Risks: Pregnant women and those with non-cancerous conditions cannot participate.