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A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus

Study on AZD6234 with incretin therapies for overweight adults.

Recruiting
18 years and older
All
Phase 3

This study looks at how well a drug called AZD6234 works and how safe it is for adults who are overweight or have obesity. It focuses on those with extra weight-related health issues, with or without Type 2 Diabetes Mellitus (T2DM). Participants will be randomly placed in groups to receive either AZD6234 or a placebo (a fake treatment) alongside their current incretin-based therapy, which is a type of diabetes medication that helps control blood sugar.

The study lasts 68 weeks and measures weight loss. **Phase III** means it's a later stage of testing to check if the drug is effective and safe. **Double-blind** means neither the participants nor the researchers know who is receiving the drug or placebo, ensuring unbiased results.

  • The study lasts 68 weeks, with multiple visits required.
  • Participants will receive either AZD6234 or a placebo.
  • Potential side effects or risks will be monitored during the study.
Study details
    Obesity or Overweight
    Weight-Related Comorbidity
    With/Without Diabetes Mellitus
    Type 2

NCT07776509

AstraZeneca

17 October 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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