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Study of Olverembatinib (HQP1351) in Patients With CML-CP

Studying Olverembatinib for patients with chronic myeloid leukemia.

Recruiting
18 years and older
All
Phase 3

This study is for patients with a type of blood cancer called Chronic Myeloid Leukemia in Chronic Phase (CML-CP). The study aims to test a new medicine called olverembatinib. In Part A, it will compare this new drug with a standard treatment called bosutinib. Part B will focus on patients with a specific change in their cancer cells, known as the T315I mutation. Some patients from Part A might switch to the new drug if they don't respond well to bosutinib.

  • Duration: The study involves a series of visits and treatments, but the exact length isn't specified.
  • Eligibility: Patients must be 18 years or older and have previously tried other treatments.
  • Risks: Patients with certain infections or allergies should not participate.

To join, you must be an adult with CML-CP and have tried other treatments. Pregnant or nursing women cannot participate. If you have specific mutations or allergies, this study might not be for you. Discuss with your doctor to see if this study is a good fit for you.

Study details
    Chronic Myeloid Leukemia
    CML
    CML
    Chronic Phase

NCT06423911

Ascentage Pharma Group Inc.

17 October 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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