This study aims to help us understand cancer better by collecting health information, blood, and tumor samples from people with stage I, II, or operable stage III cancer in certain solid tumors. Solid tumors are lumps of cancer cells that can grow in different parts of the body. This is an observational study, meaning participants will not get any special treatment from the study itself but will continue with their usual care from their doctor.

Participants will be involved for about 5.5 years and must be 18 years old or older. They should have a confirmed diagnosis of a malignant solid tumor, like certain types of bladder, esophageal, or lung cancer. The study will not include tumors like breast cancer, thyroid cancer, or blood cancers.

• Participation lasts approximately 5.5 years and involves routine follow-ups.
• No special treatment from the study; continue regular care with your doctor.
• Participants must provide blood samples and tumor tissue as part of the study.