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A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has Spread

Study of BPX-601 CAR T-cell therapy for advanced prostate cancer.

Recruiting
18 years and older
Male
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

In this study, researchers are testing a new treatment called BPX-601, a CAR-T cell therapy. CAR-T cells are special cells made from a patient's own T-cells (a type of immune cell) which are modified to fight cancer. The study focuses on prostate cancer that has come back, doesn't respond to treatment, and has spread. Scientists want to find out what side effects may occur, the best dose, and if it can effectively treat the cancer.

To join this study, participants must have advanced prostate cancer that doesn't respond to usual treatments and has spread. They need to have tried at least two other treatments. Some people won't be able to join, like those with certain bone issues or blood problems.

  • **Length & Visits:** Participants will need multiple visits for treatment and monitoring.
  • **Risks & Side Effects:** There might be unknown side effects from BPX-601.
  • **Treatment:** BPX-601 therapy involves using your own cells to fight cancer.

Note: Other criteria may apply for participation. Always discuss with your doctor to understand if this study is right for you.

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Study details
    Prostate Cancer

NCT07543055

Regeneron Pharmaceuticals

11 October 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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