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A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

Study compares Zenagamtide and Semaglutide for weight loss effectiveness.

Recruiting
18 years and older
All
Phase 3

This study is testing if a medicine called Zenagamtide helps people with extra weight lose pounds better than another medicine known as Semaglutide. The study will check if Zenagamtide is safe and if it works well for weight loss.

Glycated haemoglobin (HbA1c) is a test that shows average blood sugar levels over the past 2-3 months. If someone’s HbA1c is 6.5% or higher, they cannot join the study. People with a history of diabetes or who have used certain diabetes medicines recently also cannot participate.

  • The study is for adults aged 18 and older, both men and women.
  • Participants must not have diabetes or certain diabetes-related conditions.
  • If you've used certain diabetes medications in the past year, you cannot join.
Study details
    Overweight
    Obesity

NCT07668414

Novo Nordisk A/S

10 October 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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