**Integrating Point of Care Testing (POCT) For Newborn Screening and Early Care for Sickle Cell Disease in Yopougon, Côte d'Ivoire** Sickle cell disease (SCD) is a serious blood disorder that you inherit from your parents. It affects the red blood cells, which carry oxygen in your body. This study is looking at a new way to test and care for babies with SCD in Côte d'Ivoire. The goal is to see if using a special test called Gazelle Multispectral and starting treatment early can help babies with SCD stay healthier. Key points: - The study will last 2.5 to 3.5 years and will compare new results with old data from the region. - Babies will be tested early, and if they have SCD, they will get special care including medicines and vaccines. - Parents will learn how to take care of their baby and when to seek medical help. Children aged 0-6 months can join if they're healthy and haven't had a blood transfusion in the last 90 days. Babies already diagnosed with SCD, in another study, or very sick can't join. The study hopes to improve care and save lives in the region.