This study is testing a medicine called 3-n-Butylphthalide (NBP) for people with Multiple System Atrophy (MSA), a condition where different parts of the brain and nerves don't work well. The goal is to see if NBP helps with symptoms and is safe. A placebo, which looks like the NBP capsule but doesn't have any medicine in it, will be used for comparison.
- Duration: Participants will take NBP or placebo three times a day for 6 months.
- Visits: There will be four clinical visits for follow-up and tests.
- Diary: Participants need to keep a diary of their symptoms and medication use.
Who can join? People aged 30-80, diagnosed with MSA, who can do tests like MRI and PET-CT scans, and have been on stable medication.
Who cannot join? Those with other major brain diseases, psychiatric disorders, severe liver or kidney issues, recent bleeds, severe cognitive problems, or those who can't take medicine properly.
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