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Found 6,933 clinical trials

Featured trial
K Kate Worley

Retrospective study examining the differences in vocalizations of babies and toddlers with Rett compared to same age peers

Retrospective study examining the differences in vocalizations of babies and toddlers with Rett compared to same age peers: We are looking to recruit children and their parent(s) to participate in a study examining the early speech development of infants and toddlers later diagnosed with Rett syndrome, compared to girls their …

4-10 years Female Phase N/A
Featured trial
A Aleksys Patterson

Evaluating the Psychometric Properties of Three Clinical Trial Outcome Measures for Rett Syndrome

Evaluating the Psychometric Properties of Three Clinical Trial Outcome Measures for Rett Syndrome: The purpose of this research study is to document the psychometric properties of three non-invasive, clinic-friendly, and quantifiable outcome measures reflecting pathologically- and clinically-relevant symptoms of Rett Syndrome (RTT). Despite several ongoing or pending clinical trials for …

1 years and older All Phase N/A
Featured trial
M Maggie Davis

Caregivers' Experiences in the Transitioning from Hospital to the School Setting of Children with Special Health-care Needs

The purpose of this survey is to gather information on caregivers' perspectives and experiences with the transition process from the hospital to the school for children with special health-care needs.  The survey is anonymous, web-based survey.  Find the survey here: https://redcap.link/41o38uuc 

100 years and younger All Phase N/A
Featured trial
H Heather Hodges, MA, CCC-SLP

People With Parkinson's Disease Contributing Speech Samples for Improved Accessibility of Speech-Enabled Devices

Parkinson's affects speech, so many people find that their speech devices stop working after they get Parkinson's. We intend to make such problems a thing of the past. The Speech Accessibility Project online (SAP online) is aimed at better automatic speech recognition for people with Parkinson's Disease or who otherwise …

18 years and older All Phase N/A
Featured trial
F Fox Insight

Fox Insight - Online Parkinson's Health and Genetic Study

Fox Insight is an online study gathering health information from tens of thousands of people with and without Parkinson’s disease.  Study participation does not require any travel and all you need is an internet connection to start today at www.foxinsight.orgFox Insight volunteers are invited to take part in virtual ‘study visits’ …

18 years and older All Phase N/A
Featured trial
P PPMI Call Center

Parkinson Progression Marker Initiative Online (PPMI Online)

Parkinson Progression Marker Initiative Online (PPMI Online) is an observational study collecting participant reported information from people with and without Parkinson's disease (PD), for the goal of better understanding risk and predictive factors for PD.PPMI Online is part of the broader Parkinson Progression Marker Initiative aimed at identifying markers of …

18 years and older All Phase N/A
Featured trial

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

The objective of this Master Protocol is to evaluate the efficacy and safety of plixorafenib in participants with locally advanced or metastatic solid tumors, or recurrent or progressive primary central nervous system (CNS) tumors harboring BRAF fusions, or in participants with rare BRAF V600-mutated solid tumors, melanoma, thyroid, or recurrent …

10 years and older All Phase 2
Featured trial

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

The primary goal of this study is to assess the safety and tolerability of mRNA-4359 administered alone and in combination with pembrolizumab.

18 years and older All Phase 1/2
Featured trial
Y Yongchang Zhang, MD

Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation

The purpose of this study is to assess the Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation.

18 years and older All Phase 2
Featured trial

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

This first-in-human (FIH) trial for BNT116 aims to establish the safety profile and a safe dose for BNT116 monotherapy as well as for BNT116 in combination with approved medicinal products and/or in combination with investigational medicinal products (IMPs) including, but not limited to, cemiplimab, docetaxel, carboplatin, paclitaxel, BNT316 (an anti-cytotoxic …

18 years and older All Phase 1

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