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Found 6,931 clinical trials

J Jessica Jackson, PhD Candidate

Impact of a Biophoton Therapy on Patients With Brain Disorders

Previous clinical studies revealed that the newly developed biophoton therapy has been safe and effective in treating patients with Alzheimer's disease, dementia, stroke, traumatic brain injury, or Parkinson's disease. The current study is to confirm the previous clinical observation by conducting as a randomized, triple-blinded, placebo-controlled prospective intervention clinical research. …

18 years and older All Phase N/A
M Mark I Boulos, MD, MSc

ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing

Obstructive sleep apnea (OSA), which causes abnormal pauses in breathing during sleep, is common in patients with vascular cognitive impairment (VCI) and Alzheimer's disease (AD), and exacerbates the cognitive deficits seen in these conditions. OSA is typically treated with continuous positive airway pressure (CPAP), which has been shown to improve …

All Phase N/A
Y Yayun Lee, PhD

Influence of Autonomy on Motor Learning in People With Parkinson's Disease

The goal of this clinical trial is to explore the benefits of autonomy supported learning in patients with Parkinson's disease. The main questions to answer are:Whether autonomy supported learning can benefit motor learning in PD patientsWhether autonomy supported learning can enhance intrinsic motivation and/ or information processing of PD patients …

20 years and older All Phase N/A
C Cindel Albers

The Effect of Compensation Strategies on Gait Impairment in Parkinson's Disease

Gait disturbances are disabling and common in Parkinson's disease (PD). Patients use many different, and typically self-developed, strategies to compensate for their walking abnormalities. There is a wide variety of compensatory strategies, of which external and internal cueing are the most commonly known. External cueing refers to externally produced predictive …

18 years and older All Phase N/A
S Sheldon Yao, DO

Effects Of Osteopathic Manipulative Medicine(OMM) On Lower Extremity Muscle Characteristics In Parkinson's Disease(PD) Patients

The purpose of the study is to investigate the effects that Osteopathic Manipulative Medicine has on lower extremity muscle characteristics in PD. Muscle stiffness, range of motion, and gait will be measured.Participants will be asked to attend one in person session at the NYIT Academic Health Care Center. Participants will …

18 years and older All Phase N/A
E Elena Papamichael, PhD Cand

The Effectiveness of Mixed Reality as Interventional Tool for the Improvement on Quality of Life for People With Parkinson´s Disease.

Parkinson's disease is a chronic, neurodegenerative disease of unknown cause, affecting elderly people over the age of 60. It is the second most common neurodegenerative disease, presenting psychomotor signs and symptoms that lead to impaired functionality and quality of life in affected individuals. Mixed reality involves the delivery of digital …

60 years and older All Phase N/A
A Aynur Basaran, MD, Prof.

Action Observation and Motor Imagery Therapy in Parkinson's Disease

In recent years, motor imagery (MI) and action observation (AO) therapy strategies have been used in rehabilitation programs to increase motor learning in Parkinson's disease (PD). Visuomotor training strategies such as AO and MI therapy rely on the activity of the mirror neuron system to facilitate motor re-learning. Mirror neurons …

18-65 years All Phase N/A
C Christina Faria, PhD

Effects of Home-based High-speed Bodyweight Resistance Training in Individual With Parkinson's Disease

Exercises that involve increasing the speed of movements are beneficial for individuals with Parkinson's disease (PD) and have the potential to reduce bradykinesia and improve mobility. High-speed bodyweight resistance training is a treatment that involves increasing speed considered accessible and viable as it can be performed at any time and …

50 years and older All Phase N/A

Study on Preliminary Safety and Efficacy of the ARC-IM Therapy to Alleviate Locomotor Deficits in People With Parkinson's Disease

The purpose of this clinical trial is to assess the preliminary safety and efficacy of the ARC-IM spinal cord stimulation therapy in alleviating locomotor deficits in individuals with Parkinson's disease. The ARC-IM Therapy employs epidural electrical stimulation (EES) to modulate leg muscle recruitment, with the aim of improving mobility deficits. …

18 years and older All Phase N/A
C Cennet Sena Parlatan, pHD Cand

The Effects of Specific tDCS on Cognition in MCI

INTRODUCTION:Mild cognitive impairment (MCI) is a critical transitional stage in dementia related disorders. Dorsolateral prefrontal cortex (DLPFC), and the lateral parietal (LPC) cortex are subjected to neuropathological changes in MCI. Parietal memory network (PMN) integrity alterations and default mode network (DMN) alterations also occur in MCI. Transcranial direct current stimulation …

45-80 years All Phase N/A

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