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Found 6,914 clinical trials

W Wenbo Meng, MD,PhD

Whether Control of Serum Uric Acid (SUA) Improves Survival After Pancreatic Cancer

This retrospective study aims to analyze the impact of postoperative changes in serum uric acid (SUA) levels on the prognosis of patients undergoing pancreatic cancer resection.

18-85 years All Phase N/A
K Kaixuan Wang, MD

Establish Diagnostic Models Based on Portal Venous Blood for Pancreatic Cancer

Explore new markers based on portal venous blood sampling to establish novel diagnostic models for identification of malignant pancreatic mass.

18-80 years All Phase N/A

DESTINY-PANTUMOUR04

This study will evaluate the effectiveness of T-DXd in patients with HER2-positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have received prior systemic treatment for metastatic or advanced disease and have no satisfactory alternative treatment options in a real-world setting in the US

18-130 years All Phase N/A
Q Qiang Xie, PhD

Glucagon-like Peptide-1 Receptor PET/CT in GLP-1R Related Disease

To evaluate the potential usefulness of 68Ga/18F-Exendin 4 positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various GLP-1R-related disease patients.

18-80 years All Phase N/A
A Ali A Aghdassi, Professor

Comparison of the Physical Activity in Cancer Patients Assessed by Questionnaire and Motion Tracker

Physical activity is an important aspect of cancer therapy but correct measurement of physical activity is difficult. In this study, the physical activity of patients undergoing cancer therapy is assessed by questionnaire and by motion tracker. The results are then compared to answer whether there are differences between the two …

18 years and older All Phase N/A
L Lead Nurse

ctDNA Assay in Patients With Resectable Pancreatic Cancer

The purpose of this study is to determine the proportion of positive ctDNA -freely circulating tumor DNA fragments found in the blood plasma- in patients with pancreatic cancer and to better understand the relationship between possible ctDNA biomarkers and patient survival. A successful study may provide preliminary evidence that helps …

18-99 years All Phase N/A

MR Guidance for Liver and Pancreas

This is a single centre, single arm, prospective feasibility study that aims to see whether magnetic resonance imaging (MRI) as a source of image guidance before each radiation treatment fraction is feasible, and also if it may provide information that could potentially be used during the treatment to improve the …

18 years and older All Phase N/A
B Bin Cheng

Management of Pancreatic Cystic Lesions Using Artificial Intelligence Based on EUS and Multimodal Data

The primary objective is to construct a multimodal AI model (Cyst-AI) based on EUS images and clinical data such as imaging features(CT or MRI) and laboratory tests to assist endoscopists in the diagnosis of pancreatic cystic lesions(PCLs), mainly differentiating mucinous from non-mucinous lesions.The secondary objective is to evaluate the model's …

18 years and older All Phase N/A
H Heather Grant

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

The Marathon of Hope Cancer Centres Network (MOHCCN) is a national network of cancer centres that pursue collaborative cancer research in precision medicine (an emerging approach for disease treatment and prevention that considers individual variability in DNA, environment and lifestyle) to accelerate the discovery of innovations and improve the health …

18 years and older All Phase N/A
M Martin PETIT, MD

Effectiveness of the Transversus Abdominis Plane Block Associated With Opioid Spinal Anesthesia on Analgesia After Cephalic Duodenopancreatectomy

Duodenopancreatectomy is a major, risky surgery that causes significant post-operative pain. Optimizing perioperative analgesia remains a challenge, and requires multimodal management, notably involving locoregional analgesic techniques.The thoracic epidural helps reduce perioperative pain, as well as certain postoperative complications. However, epidural analgesia is not without effects, and the data remains quite …

18 years and older All Phase N/A

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