Found 6,935 clinical trials
Black and African American Connections to Parkinson’s Disease (BLAAC PD) Study
BLAAC PD aims to learn more about gene changes that may cause Parkinson’s in Black and African American people. This new data could lead to future Parkinson’s tests and treatments for Black and African American people. And it may help better understand disease in other groups too. You can join …
Vet-PD
The main goal of Vet-PD is to find genes that increase a person's risk of developing Parkinson's disease (PD). Genes are the basic “instruction book” for the cells that make up our bodies. Each person has approximately 60,000 genes. Small differences in these genes partly determine a person's unique physical …
Analysis of Sensory Profiles and Modulation Mechanisms in People Living with Parkinson's Disease and Comorbid Chronic Pain
Pain is a highly prevalent symptom in Parkinson Disease (PD), often experienced before the onset of motor symptoms, and aggravating as PD progresses. Previous research reports a higher sensitivity for painful stimulation and neuropathological abnormalities in different brain regions of pain processing in patients with PD but fails to explain …
PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
The Parkinson Progression Marker Initiative (PPMI) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest PD, prodromal PD, and healthy controls.The overall goal of PPMI is to …
Post Marketing Surveillance(PMS) Study of Lorviqua in Korea
The objective of this study is to monitor the usage of Lorviqua in real practice within label, including the adverse events associated with Lorviqua
Serotonin Release in Premotor and Motor PD
In this study, the investigators aim to provide a deeper understanding of Parkinson's disease and find a biomarker of Parkinson's disease. This is done using imaging scans called Positron Emission tomography (PET), Single Photon Emission Computed Tomography (SPECT), and Magnetic Resonance Imaging (MRI). The findings will provide a deeper understanding …
Longitudinal Investigation of I2BS in PD
In this study, the researchers aim to find a biomarker of PD. Using imaging scans called Positron Emission tomography (PET), Single Photon Emission Computed Tomography (SPECT), and Magnetic Resonance Imaging (MRI). The PET and SPECT scans use small amounts of radiation and specific compounds called tracers, to study chemical changes …
Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR
It is not known what causes Parkinson's disease and what makes it worsen over time. Research conducted in the past few years has highlighted the possible role of inflammation on this process but its actual mechanisms are still obscure.In this study, the investigators aim to gain understanding on how inflammation …
Immune and Genomic Markers in ALK+ NSCLC
The purpose of this research study is to obtain and study clinical history, and tissue and saliva specimens if available from participants with Anaplastic Lymphoma Kinase-ALK+ Non-Small Lung Cancer(NSCLC)
Caring for Children with Genetic Conditions
This is a survey-based study that will investigate the current use of children's books on genetic conditions by families of pediatric patients with various genetic conditions, and by genetic counselors in clinic. This survey is for primary caregivers of children with genetic conditions. If interested in participating, contact:Katherine StevensPhone: 207-616-8042Email: …
